Method
Yoy · gp.fundamentals.revenue
Raw value 66.86% · CORE
· Pharmaceutical Preparations
RESEARCH SNAPSHOTALNYLAM PHARMACEUTICALS, INC.'s latest supported as-filed period reports revenue of $1.3B, 66.9% above the comparable as-filed period. Every value below links to its SEC accession and metric lineage.
No material rule-based research observation currently meets GrossPattern's Insight value threshold. Current state, direction, and filing evidence remain available below.
A multidimensional view of the latest comparable filing—not a composite score or recommendation.
Yoy · gp.fundamentals.revenue
Raw value 66.86% · CORE
Level · gp.fundamentals.inventory_revenue_ratio
Raw value 7.52% · OPTIONAL
Level · gp.fundamentals.gross_margin
Raw value 76.90% · CORE
Level · gp.fundamentals.operating_margin
Raw value 17.93% · CORE
Ratio · gp.fundamentals.rnd + gp.fundamentals.revenue
Raw value 32.00% · OPTIONAL
Level · gp.fundamentals.sbc_revenue_ratio
Raw value 6.71% · OPTIONAL
Business direction, financial quality, capital allocation, and governance evidence remain separate—never collapsed into a recommendation score.
Interpretation boundary Direction describes measurable company fundamentals. Governance reports observable evidence only; it does not grade management character or predict stock returns.
Latest available comparable states within 180 days, normalized with robust median/MAD statistics.
The most important deterministic changes, ranked by magnitude, issuer history, persistence, and accounting profile.
Cash & equivalents changed +53.4% from the comparable as-filed period. The change ranks at the 74th percentile of 217 prior comparable changes.
Inventory changed +35.5% from the comparable as-filed period. The change ranks at the 70th percentile of 50 prior comparable changes.
Net income changed +348.2% from the comparable as-filed period. The change ranks at the 99th percentile of 167 prior comparable changes.
Each point keeps the date investors could first observe it and its accession.
ALNY · as filed with the SEC · reported-date aware
Direct SEC links, filing dates, report periods, and amendment flags.
0001178670-26-000062SEC ↗8-KJul 30, 2026Period Jul 30, 20260001178670-26-000060SEC ↗4Jun 3, 2026Period Jun 1, 20260001178670-26-000048SEC ↗4Jun 3, 2026Period Jun 1, 20260001178670-26-000047SEC ↗8-KMay 27, 2026Period May 20, 20260001628280-26-038499SEC ↗4May 22, 2026Period May 20, 20260001178670-26-000042SEC ↗4May 22, 2026Period May 20, 20260001178670-26-000041SEC ↗Transaction semantics distinguish purchases, sales, awards, exercises, withholding, and derivatives.
| Filed / transacted | Reporting owner | Semantics | Shares | Price | Notional | Source |
|---|---|---|---|---|---|---|
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E IDirector | Option ExerciseDirect | 3,830 | $0 | $0 | Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E IDirector | Open Market SaleDirect | 921 | $298 | $274,191 | Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E IDirector | Open Market SaleDirect | 1,175 | $299 | $351,219 | Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E IDirector | Open Market SaleDirect | 1,222 | $300 | $366,441 | Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E I |
GrossPattern stores immutable raw artifacts, accession-scoped facts, parser and metric versions, dependency edges, quality state, and channel-specific publication rights. A restricted or unknown ancestor blocks the page and API automatically.
SEC source policy ↗Operating income changed +1528.7% from the comparable as-filed period. The change ranks at the 98th percentile of 133 prior comparable changes.
Operating margin changed +2002 basis points from the comparable as-filed period. The change ranks at the 21th percentile of 61 prior comparable changes.
Research & development changed +27.7% from the comparable as-filed period. The change ranks at the 65th percentile of 133 prior comparable changes.
Revenue changed +66.9% from the comparable as-filed period. The change ranks at the 48th percentile of 61 prior comparable changes.
Method note “Materiality” here is an analytical magnitude band, not a legal conclusion. Full filing-text semantic changes remain unpublished while excerpt rights and review thresholds are unresolved.
Latest supported period in this snapshot: 2026-06-30. Duration facts use direct quarterly or annual SEC contexts; GrossPattern does not manufacture missing Q4 values.
0001178670-26-000040| Open Market SaleDirect |
| 495 |
| $301 |
| $148,856 |
| Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E IDirector | Open Market SaleDirect | 17 | $303 | $5,145 | Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | PYOTT DAVID E IDirector | Option ExerciseDirect | 3,830 | $0 | $0 | Form 4 ↗ |
| Jun 1, 2026Filed Jun 3, 2026 | Cravatt BenjaminDirector | Grant Or AwardDirect | 4,393 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | Sigal Charles ElliottDirector | Grant Or AwardDirect | 671 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | Sigal Charles ElliottDirector | Grant Or AwardDirect | 1,441 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | SCHULMAN AMY WDirector | Grant Or AwardDirect | 838 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | SCHULMAN AMY WDirector | Grant Or AwardDirect | 1,802 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | Reitan Colleen FDirector | Grant Or AwardDirect | 671 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | Reitan Colleen FDirector | Grant Or AwardDirect | 1,441 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | PYOTT DAVID E IDirector | Grant Or AwardDirect | 671 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | PYOTT DAVID E IDirector | Grant Or AwardDirect | 1,441 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | KELLOGG PETER NDirector | Grant Or AwardDirect | 671 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | KELLOGG PETER NDirector | Grant Or AwardDirect | 1,441 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | HAMBURG MARGARET ADirector | Grant Or AwardDirect | 671 | $0 | $0 | Form 4 ↗ |
| May 20, 2026Filed May 22, 2026 | HAMBURG MARGARET ADirector | Grant Or AwardDirect | 1,441 | $0 | $0 | Form 4 ↗ |